Question 7 2 pts During rigor: Myosin remains tightly bound to actin until ATP b

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Question 7 2 pts During rigor: Myosin remains tightly bound to actin until ATP becomes available. Myosin unbinds from actin due to the presence of ATP ATP is hydrolyzed and split into ADP+P Release of Pi causes the myosin head to rotate and pull on the thin filament. A. Myosin releases ATP. Question 8 2 pts Following a single electrical excitation, when calcium is being released from the SR at a rate greater than it is being pumped back into the SR: relaxation occurs contraction occurs and force will be generated. it will always result in complete tetanus. myosin will be unable to bind to actin. an EPSP is produced,

Explanation / Answer

7. During rigor:

Myosin remains tightly bound to actin until ATP becomes available.

For relaxation of muscle, i.e. for detachment of myosin head and actin, ATP is a must. Without ATP, myosin head remains bound to actin in a contracted manner, thus causing rigor.

8. Following a single electrical excitation, when calcium is being released from the SR at a rate greater than that is being pumped back into the SR:

contraction occurs and force will be generated

When excess calcium remains in the sarcoplasm, that removes the inhibition of tropomyosin, binds to the troponin-C and exposes actin to bind with myosin. this results in myosin-actin binding, contraction and generation of force.

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