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Which one of the following statements about cross-bridge cycling is true? a. The

ID: 3509624 • Letter: W

Question

Which one of the following statements about cross-bridge cycling is true? a. The detachment of the myosin head from actin is the Ca2+-dependent step of the cross- b. Hydrolysis of ATP is followed immediately by release of the reaction products, ADP and O C.The binding affinity of the myosin head for actin is lowest when there are no nucleotides d. All else being equal, a myosin isoform with a longer neck region, i.e., the part between the bridge cycle. inorganic phosphate. bound to myosin, higher when ADP is bound, and highest when ATP is bouno. head and the shaft of the thick filament, will cause faster filament sliding than a myosin isoform with a shorter neck region.

Explanation / Answer

The following statement is true regarding cross bridge cyclng:

c. The binding affinity of the myosin head for actin is lowest when there are no nucleotides bound to myosin, higher when ADP is bound, and highest when ATP is bound.

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