This assignment will assess the competency 6. Explore diseases and disorders of

Question

This assignment will assess the competency 6. Explore diseases and disorders of the cardiovascular and lymphatic systems. (Ch.12)

Directions: Your assignment will be to summarize the case study presented. Use critical thinking and apply what you have learned in this chapter to answer questions 1 through 3 about this case.

Case Study:
A 72-year-old man, Robert Brown, has been diagnosed with chronic myeloid leukemia. Robert has been told he has less than 1 year to live. His oncologist says that stem cell transplantation may help him. He refuses any treatment. His spouse is begging him to please attempt the stem cell transplantation. After testing, his 23-year-old daughter is found to be the best match for him. Robert, however, still does not want to undergo the treatment and refuses to let his daughter be the donor. No other match is found.

1. What is the prognosis for Robert if he is the “typical” case of chronic myeloid leukemia? Identify the prognosis should he agree to the stem cell transplant.
2. What suggestions, if any, do you have for his spouse and daughter?
3. If his daughter were to become a donor for Robert, what preparation would she need?

Your paper should be at least 1 page in length, double-spaced, 12-pts. Times New Roman font with proper spelling and grammar. Your paper should include APA style in-text citations and references.

Explanation / Answer

1.One large study of CML patients treated with imatinib (Gleevec®) found that about 90% of them were still alive 5 years after starting treatment. Most of these patients had normal white blood cells and chromosome studies after 5 years on the drug.

4567

Learning that you have cancer can be overwhelming. But statistics show positive survival rates for those with chronic myeloid leukemia.

Understanding chronic myeloid leukemia

Chronic myeloid leukemia, or CML, is a type of cancer that begins in the bone marrow. It develops slowly in the blood-forming cells inside the marrow, and eventually spreads through the blood. People often have CML for quite some time before noticing any symptoms or even realizing they have cancer.

CML seems to be caused by an abnormal gene that produces too much of an enzyme called tyrosine kinase. Although it’s genetic in origin, CML is not hereditary.

Phases of CML

There are three phases of CML:

Treatment options

During the chronic phase, treatment usually consists of oral medications called tyrosine kinase inhibitors or TKIs. TKIs are used to block the action of the protein tyrosine kinase and stop the cancer cells from growing and multiplying. Most people who are treated with TKIs will go into remission.

If TKIs aren’t effective, or stop working, then the person may move into the accelerated or blastic phase. A stem cell transplant or bone marrow transplant is often the next step. These transplants are the only way to actually cure CML, but there can be serious complications. For this reason, transplants are typically only done if medications aren’t effective.

Prognosis

Like most diseases, the prognosis for those with CML varies according to many factors. Some of these include:

Overall survival rates

Cancer survival rates are typically measured in five-year intervals. According to the National Cancer Institute, overall data shows that almost 65.1 percent of those who are diagnosed with CML are still alive five years later.

2.If he doesn't want to undergo bonemarrow transplantation, they also start chemotherapy,which is also a effective treatment.

3.If she decide to donate, the process and possible risks of donating will be explained to her. she will then be asked to sign a consent form. she can choose to sign or not. You won't be pressured to sign the form.

After she agrees to be a donor, she'll have a test called human leukocyte antigen (HLA) typing. HLAs are proteins found in most cells in your body. This test helps match up donors and recipients. A close match increases the chances that the transplant will be a success.

If she sign up with a donor registry, she may or may not be matched with her father who needs a blood stem cell transplant. However, if HLA typing shows that they are a match, you'll undergo additional tests to make sure she doesn't have any genetic or infectious diseases that can be passed to the transplant recipient. her doctor will also ask about your health and your family history to make sure that donation will be safe for her.

. If you're identified as a match for someone who needs a transplant, the costs related to collecting stem cells for donation will be paid by that person or by his or her health insurance.but in this case that is not gonna happen.

Related Questions

Navigate

• Browse (All)
• Browse T
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.