1.describe the disease process for atherosclerosis. 2. Describe how the followin
ID: 3507024 • Letter: 1
Question
1.describe the disease process for atherosclerosis.2. Describe how the following will affect blood pressure( go up and down) and state why you predict that . - stressful job - diet high in sodium - brain damage to the vasomotor center - severe, long term dehydration
3. Rh factor/ pregnancy/ erythroblastosis fetalis- when to be concerned and when not to be and why
1.describe the disease process for atherosclerosis.
2. Describe how the following will affect blood pressure( go up and down) and state why you predict that . - stressful job - diet high in sodium - brain damage to the vasomotor center - severe, long term dehydration
3. Rh factor/ pregnancy/ erythroblastosis fetalis- when to be concerned and when not to be and why
2. Describe how the following will affect blood pressure( go up and down) and state why you predict that . - stressful job - diet high in sodium - brain damage to the vasomotor center - severe, long term dehydration
3. Rh factor/ pregnancy/ erythroblastosis fetalis- when to be concerned and when not to be and why
Explanation / Answer
1. Atherosclerosis is process of deposition of atheromatous plaque with vascular changes in blood vessel. The process starts with endothelial injury, which induce recruitment of monocyte in subendothelial space. Monocyte convert to macrophages, which then take up oxidized LDL and VLDL. This convert macrophages into foam cell. They latter release inflamatoinf mediators that induce proliferation on smooth muscle. Connective tissue may deposit over it. This lead to formation of atheromatous plaque which invades lumen of vessel.
2. Stressful job - blood pressure will increase (stressful job will require increase in blood flow to various organs such as muscle, this is achieved by increasing blood pressure).
3. When mother is Rh - (negative) and father is Rh + and her first child was Rh +. The Rh + pregnancy exposes maternal body to Rh antigen from fetal blood. This lead to production of Anti Rh + antibody (Rh - blood doesn't contain any Rh antigen under normal condition therefore if exposed to Rh+ antigen then anti Rh antibodies will be formed). These antibody will cross placenta during second pregnancy and will attack fetal Rh+ RBC, this will lead to Erythroblastosis fetalis. Therefore for prevention of such event pregnant mother is given Anti D injection
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