ontrol Questions 7-10 Before After Plot x EPP size (mV) Chd EPP size (mV) mEPP s

Question

ontrol Questions 7-10 Before After Plot x EPP size (mV) Chd EPP size (mV) mEPP size (mV) Question 7: What does the left-most column in plot x indicate? (see arrow in plot x above) b.The number of times no vesicle was released, even though the presyna he number of times more than one synaptic vesicle was released when the presynaptic nerve was stimulated ptic nerve was stimulated imulated The number of times a single vesicle was released when the presynaptic nerve was st nerve was stimulated The number of times the muscle cell depolarized when the presynaptic Question & most column in plot x (see arrow in plot x above)? :Which quantal analysis term is used to indicate what is counted in order to get the values in that left Units b. Vesicles d. Failures Question 9: The data for questions 7-10 were recorded from a muscle cell at one neuromuscular junction before (left) and after (right) an experimental manipulation that changed the strength of this synapse. Based on what we discussed in class, strength? Assume ealy one thing changed to cause these results a. A larger number of acetyicholine (ACh) molecules were released from the synaptic vesicles of the following could be a valid explanation for what caused this change in synaptic A smaller number of acetylcholine (ACh) molecules were released from the synaptic vesicles d. c.There was an increase in the number of postsynaptic ACh receptors There was a decrease in the number o There was an increase in the number of synaptic vesicles released when the presynaptic neuron was mulated There was a decrease in the number of synaptic vesicles released when the presynaptic neuron was stimulated Question 10 Which of the following variables is/are affected by the concentration of Ca* in the solution around the neuromuscular junction in these experiments? There may be more than one correct answer, select all that a. n None of the above is affected by concentration of Ca2

Explanation / Answer

Question 7

The left column indicates the number of times no vesicle was released, even though the presynaptic nerve was stimulated.

It can be seen that the end plate potential (EPP) of a very small size was applied into the cell(a few mV, which may be less than threshold), and there is very high number of such EPPs applied.

Hence, it can only be the number of times no vesicle was released, even though the presynaptic nerve was stimulated.

Hence, the correct answer is b.

Question 8

The counts of the above values (in Question 7) are termed as failures in quantal analysis.

Since, no vesicle is being released,even after supplying a potential, the experiment can be designated as failure.

Hence, the correct answer is d

Question 9

Such a change in synaptic strength can be brought on by only one factor which is:

increase in the number of postsynaptic Ach receptors.

Since, the response of the cell to low intenity stimuli is also seen now, and that to the high-intensity stimuli is increased further, we can conclude that the number of postsynaptic Ach receptors have increased.

Hence, the correct option is c.

Question 10

There is only one variable affected by the concentration of Calcium around the junction, which is p.

Hence, the correct choice is b.

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