Section UNIT Date 21 Check Your Understanding Critical Thinking and Application

Question

Section UNIT Date 21 Check Your Understanding Critical Thinking and Application Questions REVIEW 1 Nilesh has Hodgkin's lymphoma, a cancer that primarily involves lymphocytes As part of his treatment plan, he is undergoing surgery to remove his spleen, a procedure called a splenectomy, and several affected cervical lymph nodes. a How does the role of the spleen differ from the role of lymph nodes? b What potential complications might Nilesh face without a spleen? Explain. c How would the complications in part b differ from potental suses resulting from removal of multiple cenvical lymph nodes? The condition aplastic anemia is characterized by complete failure of the bone marrow to produce formed elements of the blood due to damaged hematopoietic stem cells. Explain how aplastic anemia would affect the immune response 21 Explain why blockage or removal of the lymphatic vessels can result in significant edema (accumulation of fluid in a limb or body part). 3 Lymphatics and ImmunityUNIT 21 577

Explanation / Answer

1. a) spleen filters blood as a part of immune system and RBCs are recycled here. Lymph nodes filter lymph and builds immune response.

b) As spleen is where RBCs are recycled, removal of spleen affects this process and also the body becomes more prone to infections as spleen has immune functions too.

c) with removal of some lymph nodes, lymphatic fluid accumulates and can cause swelling. However the immunity won't be affected much as there are other lymph nodes.

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