Hypothermia occurs when core body temperatures body temperatures f hypothermia o

Question

Hypothermia occurs when core body temperatures body temperatures f hypothermia often results from nervous system One possi signals in neurons (and also cardiac fall well below the normal 37°C. As core all, so does diffusion rate, as demonstrated by the first exercise. Death from failure (which can have a number of causes). ble cause is that lowering the temperature can affect the propagation of electrical cells).Neurons have special Na channels that are only open 0.5 msec. During this short time, Na is allowed to diffuse down its concentration gradient. At normal body temperature, enough sodium diffuses into the cell to cause a voltage change of approximately 80 m V across the cell membrane 2. How many seconds is 0.5 msec? 0.05 msec .OGIS00665 second 3. Mechanistically explain why Na* isn't able to diffuse without the help of a channel protein Ala4 ljan lon tna 11e(rmirti. ) wmau he nel p o chamel prote FOC1H04edn iped ymemotane t if mmbrane 4. Does Na" move into the cell by simple or facilitated diffusion? S. Based on he itesults of the first experiment, calculate the approximate voltage change from a Na channel that was open 0.5 msec. i) at room temperature ii) at ice water temperature

Explanation / Answer

5. i) Here the voltage change will be 80mV as it is mentioned in the text only that the voltage change across cell membrane at normal body temperature is 80mV. The body temperature is normal (37 degree celcius) at room temperature.

6. The temperature of ice water is zero degree celcius. The voltage change will be very less than the normal value as the diffusion rate decreases with decrease in temperature. You can approximate it from the value of rate of diffusion at different temperature in your first experiment. For example if rate of diffusion will become half at zero degree than the value of voltage change will decrease accordingly that is the voltage change will be approximate 40mV.

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