1. WHICH OF THE FOLLOWINGS CREATES A BRAIN LESION BY STIMULATION NEURONS TO DEAT
ID: 3490238 • Letter: 1
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1. WHICH OF THE FOLLOWINGS CREATES A BRAIN LESION BY STIMULATION NEURONS TO DEATH: A) experimental ablation B) 6-hydroxy dopamine C) sham lesion D) kainic acid 32. WHICH OF THE FOLLOWINGS CREATES A BRAIN LESION BY REMOVAL OR DESTRUCTION OF TISSUES: A) experimental ablation B) 6-hydroxy dopamine C) sham lesion D) kainic acid 33. WHICH OF THE FOLLOWINGS CREATES A BRAIN LESION BY SPECIFICALLY KILLING DOPAMINERGIC NEURONS: A) experimental ablation B) 6-hydroxy dopamine C) sham lesion D) kainic acid 34. METABOLIC ACTIVITY OF REGIONS OF BRAIN CAN BE REVEALED BY: A) a CT scan B) a 2 DG pet scan C) measuring FOS protein D) retrograde labeling method 35. WHICH OF THE FOLLOWING METHODS MEASURES EMOTIONS: A) rotarod B) morris water maze C) forced swim test D) tail flick assay 36. WHICH OF THE FOLLOWING METHODS IS A SENSORY TEST: A) forced swim test B) morris water maze C) rotarod D) tail flick assay 37. WHICH OF THE FOLLOWING METHODS IS A LEARNING AND MEMORY TEST: A) rotarod B) morris water maze C) forced swim test D) tail flick assay 38. wHiIcH OF THE FOLLOWING METHODS IS A LEARNING AND MEMORY TEST: A) rotarod B) place preference test C) forced swim test D) tail flick assay 39, WHICH OF THE FOLLOWING METHODS IS A LEARNING AND MEMORY TEST: A) rotarod B) radial arm maze C) forced swim test D) tail flick assay 40. WHICH OF THE FOLLOWING METHODS IS A MOTOR FUNCTION TEST: A) forced swim test B) morris water maze C) rotarod D) tail flick assayExplanation / Answer
31. The answer is Option D, kainic acid. Large doses of kainic acid tends to overstimulate the neurons to death. It thus injected in laboratory animals to study the effects of neuronal damage.
32. The answer is Option A, experimental ablation. Ablation involves the surgical removal of tissues from the brain. In some cases however, ablation would not involve a complete removal of the tissues as such but leaving the damaged tissues in their place.
33. The answer is Option B, 6 hydroxy dopamine. As the name suggests, it is a synthetic compound that is toxic to and destroys dopaminergic and noradrenergic neurons in the brain.
34. The answer is Option C, measuring the fos protein. The fos protein is an expression of the brain’s metabolic activity at the cellular level.
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