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16. Increasing Atrial natriuretic peptide (ANP) levels will result in? a) Vasodi

ID: 3483197 • Letter: 1

Question

16. Increasing Atrial natriuretic peptide (ANP) levels will result in?

     a)      Vasodilation of the afferent arterioles of the kidney

     b)      Decreased renin release

     c)      Increase in angiotensin II levels

     d)     a and b are correct

17. Increasing Aldosterone levels will result in?

     a)        Increased osmolarity of the urine

     b)       Decreased blood pressure

     c)       Decreased blood sodium levels

     d)       Increased blood pressure

18. Which of the following would cause a decrease in the secretion of ADH?

     a)        Increased osmolarity of blood

     b)        Decreased blood pressure

     c)        Decreased osmolarity of blood

     d)       Increased blood pressure

19. Which of the following would be expected to cause renal glomerulus filtration rate (GFR) to increase?

     a)       Dilation of the afferent arteriole

     b)       Stimulation of sympathetic activity

     c)       Constriction of the afferent arteriole

     d)       None of the above are correct

20. The function of the Vasa Recta is

     a)       Establish the osmolarity gradient in the cortex

     b)       Establish the osmolarity gradient in the medulla

     c)       Maintain the osmolarity gradient in the cortex

     d)       Maintain the osmolarity gradient in the medulla

Explanation / Answer

16. Increasing Atrial natriuretic peptide (ANP) levels will result in

           d)     a and b are correct

ANP secretion increases when ECF volume increases and atria are stretched. They act on the kidneys to increase Na+ excretion by dilating afferent arterioles and relaxing mesangial cells and also, inhibit Na+ reabsorption in the tubules. They also decrease renin release.

17. Increasing Aldosterone levels will result in

             d)       Increased blood pressure

Aldosterone increases the reabsorption of Na+ from the urine, and increases Na+ in the ECF. This is done by acting on the principal cells (P cells) of the collecting ducts, thus decreasing osmolarity of urine, increasing blood Na+ and increasing blood pressure.

18. Which of the following would cause a decrease in the secretion of ADH?

  c)        Decreased osmolarity of blood

Decreased osmolarity of blood inhibits the osmorecetors of hypothalamus, thus inhibiting the supraoptic and paraventricular nuclei of hypothalamus, and decreased ADH secretion.

19. Which of the following would be expected to cause renal glomerulus filtration rate (GFR) to increase?

     a)       Dilation of the afferent arteriole

The dilation of afferent arteriole and constriction of efferent arteriole increases the glomerular filteration pressure, thus increasing the GFR.

20. The function of the Vasa Recta is

     d)       Maintain the osmolarity gradient in the medulla

Urine concentraing mechanism is dependent upon the medullary interstitial osmolarity. This gradient is established by countercurrent multipliers present in the loops of Henle and maintained by the countercurrent exchangers of the vasa recta.

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