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Fred, a 68 y/o male who had an MI in April, 2015 was seen by his physician on Au

ID: 3483047 • Letter: F

Question

Fred, a 68 y/o male who had an MI in April, 2015 was seen by his physician on Aug. 30, 2017 presenting with shortness of breath, fatigability, and swelling of the lower extremities. Upon physical examination, the man was found to have distended jugulars and pitting edema of the ankles. His breathing was rapid (20 breaths/min) and pulmonary crackles were heard bilaterally in the lower lobes of the lungs. He had a pulse rate of 110 beats/min and a BP of 152/98. Since his MI, he was taking digoxin and hydrochlorothiazide. At the time, the Px blood and urine work showed:

     

Blood

Values

Urine

Values

Na+ (mEq/L)

128

Na+ (mEq/L)

110

K+ (mEq/L)

3.9

K+ (mEq/L)

80

Mg2+ (mg/dL)

1.7

Mg2+ (mg/day)

19

Ca2+ (mg/dL)

8.9

Ca2+ (mg/day)

105

HCO3 (mEq/L)

30

HCO3

1.7

Creatinine (mg/dl)

1.7

Creatinine (mg/L)

2080

PAH (mg/ml)

0.013

PAH (mg/ml)

5.91

Glucose (mg/dL)

85

Glucose

0

BUN (mg/dL)

14

24hr volume (L)

1.2

pCO2 (mmHg)

45

Osmolarity (mOsm/L)

750

pH

7.31

pH

6.8

The Px was admitted at that time and was treated with 2L of 5% saline and Lasix® which removed the excess blood volume. The Px’s blood pressure, heart rate and respiratory problems were reduced. Additional lab tests indicated that the Px was experiencing left ventricular failure. Once he was stable, the Px was sent home on Sept. 2.

On Dec. 7, 2017, the Px was transported to the ER via ambulance after his daughter found him unresponsive. She told the ER physician that her father had been extremely fatigued at any level of effort, had extensive flank pain and that his mental alertness had decreased significantly over the past two weeks.   Physical examination finds that the Px is doesn’t respond to questioning and appears to fall asleep during the examination. Once again, the Px exhibits excessive swelling in the lower extremities with distended jugulars. His heart rate is now 92 and irregular, his BP is 164/110. His breathing is 28 breaths/min and shallow but lung sounds are normal. His urine is dark and foamy. The ends of his fingers and toes have a bluish appearance and his abdomen is large and distended. Blood and urine values are:    

Blood

Values

Urine

Values

Na+ (mEq/L)

118

Na+ (mEq/L)

310

K+ (mEq/L)

2.9

K+ (mEq/L)

108

Mg2+ (mg/dL)

0.7

Mg2+ (mg/day)

29

Ca2+ (mg/dL)

5.9

Ca2+ (mg/day)

155

HCO3 (mEq/L)

29

HCO3

13.9

Creatinine (mg/dl)

2.2

Creatinine (mg/L)

1590

PAH (mg/ml)

0.013

PAH (mg/ml)

5.91

Glucose (mg/dL)

85

Glucose

0

pCO2 (mmHg)

53

Osmolarity (mOsm/L)

400

pO2 (mmHg)

67

24hr urine volume (mL)

600

pH

7.28

pH

6.8

RBC count / µL

3.8 x 106

Hemoglobin gm/dl

9.5

The attending physician immediately gave the Px 30 mg of propranolol and admitted the Px. An echocardiogram was conducted and showed right and left ventricular cardiomegaly.

What does the RBC and hemoglobin data indicate? What is the cause?

Blood

Values

Urine

Values

Na+ (mEq/L)

128

Na+ (mEq/L)

110

K+ (mEq/L)

3.9

K+ (mEq/L)

80

Mg2+ (mg/dL)

1.7

Mg2+ (mg/day)

19

Ca2+ (mg/dL)

8.9

Ca2+ (mg/day)

105

HCO3 (mEq/L)

30

HCO3

1.7

Creatinine (mg/dl)

1.7

Creatinine (mg/L)

2080

PAH (mg/ml)

0.013

PAH (mg/ml)

5.91

Glucose (mg/dL)

85

Glucose

0

BUN (mg/dL)

14

24hr volume (L)

1.2

pCO2 (mmHg)

45

Osmolarity (mOsm/L)

750

pH

7.31

pH

6.8

Explanation / Answer

Cardiomegaly is a medical condition in which the heart is enlarged. The most common causes are hypertension, coronary artery disease, and congestive heart failure.

The major signs and symptoms are palpitations, severe shortness of breath, chest pain, swelling in extremities, increased abdominal girth, fatigue, fainting, and abnormal pulmonary sounds.

Patient was diagnosed right and left cardiomegaly by ECG.The patient signs n symptoms clearly indicate the typical features of cardiomegaly. The patients with enlarged heart (cardiomegaly) are also at risk of developing blood clots inside the the heart lining. If the clots break free, they can travel to another part of the heart, the brain, or the lungs endangering the patient.

The normal range of RBC count in men is 4.7 to 6.1 million cells /up, and hemoglobin is 13.8 to 17.2 grams per definite. The patient hamatological reports says the decreased RBC counts and hemoglobin levels.

The lab data obviously shows that the patient had a complications of blood clot. The symptoms of bluish discoloration (cyanosis), shows that the patient may have affected by the pulmonary embolic phenomenon. The brain embolic phenomenon shows the decreased mental alertness.

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