Hi, I have a question about abnormal sodium channels. There can be more than one

Question

Hi, I have a question about abnormal sodium channels. There can be more than one answer possible on this problem:

If a skeletal muscle cell contains voltage-gated sodium channels that "hang open" a few milliseconds longer than normal (i.e.they are slow to inactivate), which of the following might result? The contraction would be longer DHP would be in contact with RyR longer More calcium would leave the sarcoplasmic reticulum than normal More ATP than normal would be broken down by the myosin heads More ATP than normal would be used by SERCA More potassium than normal would be in the extracellular fluid after repolarization The size of the overshoot would be larger More ATP than normal would be used by Na/K pumps More powerstrokes than normal would occur within the affected cell The contraction should be both longer and stronger than normal

Explanation / Answer

the contracton would be longer

more calcium would leave the sarcoplasmic reticulum

more ATP would be broken down by myocin head

more atp used by Na/K pumps

contraction should be both longer and stronger than normal

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