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Gasping for Air John, the assistant expedition leader and a seasoned alpinist, h

ID: 3479229 • Letter: G

Question

Gasping for Air

John, the assistant expedition leader and a seasoned alpinist, helped Tom guide Mark down the steep trail. Mark's breathing, increasingly labored with every passing moment, was loud enough to worry Emily and Pete, the expedition's final climber.

"Geez, do we sound like that?" gasped Pete. "I mean, I'm out of breath, too, but he sounds horrible!" "No, we're not that bad. Remember, that's why we spent the prep month at 15,000 feet. Mark was with us, so he experienced the same physiological changes we did. This," Emily nodded at Mark, "is some sort of problem."

Part II Questions

Fill in the following table about the hormone that was released when the expedition spent their prep month at 15,000 feet.

Source of Hormone Stimulus for Release Target TissuePhysiological Hormone Response

Explanation / Answer

Erythropoetin hormone.

It is secreted from kidney cell in response to cellular hypoxia

It acts on bone marrow of bone and stumulate production of red blood cell.

It increase production of red blood cell by targeting CFU -E ,proerythroblast and basophilic erythroblst differentiation.

It stimulate production of red blood cell by preventing apoptosis

It also stimulate angiogenesis and vasoconstriction dependent hypertension