This is a graded discussion: 10 points possible due Nov 5 Unit 2: Muscular Disor

Question

This is a graded discussion: 10 points possible due Nov 5 Unit 2: Muscular Disorders Our discussion will focus on disorders that affect single or groups of skeletal muscles. For instance, individuals who suffer from polio can develop muscle weakness and atrophy and some individuals may die due to respiratory paralysis. Relate how muscle fibers function in the symptoms exhibited by infected patients. Each student should focus on one aspect of a disorder, such as polio, amyotrophic lateral sclerosis, botulism (or cosmetic BOTOX injections), myasthenia gravis, muscular dystrophy, myositis, Then, as the discussion presentations develop, each should reply by adding additional information, insights, or directed questions to the initial posting person. The initial posting person is responsible for modulating the replies in his or her 'area of expertise'. or mitochondrial myopathies.

Explanation / Answer

I would like to describe about myasthenia gravis. Myasthenia gravis is an autoimmune disorder in which auto antibodies are formed against the nicotinic acetylcholine receptors. This blocks the conduction of nerve impulse from the nerves to the muscle fibers. The most commonly affected muscles are those of the eye and face resulting in drooping eyelids. The diagnosis can be made by edrophonium test. The treatment includes anti-acetylcholine esterase inhibitors (pyridostigmine), atropine, plasmapheresis, intravenous immunoglobulins, prednisone and thymectomy.

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