Question 7 0 out of 2 points Match each perturbation of the skeletal muscle cont

Question

Question 7 0 out of 2 points Match each perturbation of the skeletal muscle contraction cycle with the consequences it would cause. Each answer can be used only once. Question Selected Match Remove all ATP from the muscle fiber. A. Actin would remain bound to myosin, the rigor state would be maintained. Mutate mysoin so that it would not be able to hydrolyze ATP and produce Pior ADP C. tropomyosin would block actin-myosin binding site, power stroke would not occur B. Myosin would be able to release actin, but would not be able to rebind to actin to create a weak cross-bridge Deplete muscle cells of intracellular calcium All Answer Choices A. Actin would remain bound to myosin, the rigor state would be maintained. B. Myosin would be able to release actin, but would not be able to rebind to actin to create a weak cross- bridge C. tropomyosin would block actin-myosin binding site, power stroke would not occur

Explanation / Answer

The correct matches are:

If all ATP is removed from muscle fiber, then actin would remain bound to myosin. This would maintain the rigor state. The attachment of ATP to myosin will enable the myosin to release actin.

If the myosin is mutated so that it cannot hydrolyze ATP to produce ADP and Pi, the actin molecule is released but the cycle cannot be continued. The actin myosin bridge cannot be formed again.

If the muscle cells are depleted of intercellular calcium, tropomyosin is affected. Tropomyosin would block the actin myosin binding site. The power stroke would not occur.

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