Review the mechanisms for neurotransmitter release from the hair cells of the au

Question

Review the mechanisms for neurotransmitter release from the hair cells of the auditory system by completing each sentence afferent organ of Corti tectorial membrane The receptor cells of the auditory system are called and they are contained within a structure known as the These cells are receptors of the type known as ated Ca2* and they have hair-like protruding from one VO end repolarize vestibulocochlear nerve action potentials tip links cation hair cells lutamate stereocilia depolarization basilar membrane One inner ear membrane called the overlies the organ of Corti As pressure waves displace another membrane called the the hair cells move against the stationary tectorial membrane causing the stereocilia to bend When bent towards the tallest member of a bundle, fibrous connections called pull open mechanically gated channels. Opening of these channels leads to of the membrane, which in turn, opens channels near the base of the hair cell. onsequently, the neurotransmitter is released onto neurons leading to the generation of The axons of these neurons form the cochlear branch of the (cranial nerve VII) mechanorece Finally, bending the hair cells in the opposite direction slackens the tip links, closes the channels, and allows the cells to Reset

Explanation / Answer

1.The receptor cells of the auditory system are called HAIR CELLS contained within a structure known as ORGAN OF CORTI.

2.These cells are the receptors of the type known as MECHANORECEPTORS.They have hair like STEROCILIA protrude from one end.

3.One inner ear membrane called TECTORIAL MEMBRANE over lies the organ of corti.

4.As pressure waves displace another membrane called BASILAR MEMBRANE the hair cells move against the tectorial membrane causing sterocilia to bend.

5.When bend towards the tallest member of the bundle fibrous connection called as TIP LINKS pull open mechanically gated CATION channels .

6.Opening of these channels leads the DEPOLARIZATION of the membrane which in turn opens the VOLTAGE GATED CALCIUM channels at the base of the hair cell.

7.Consequently the neurotransmitter GLUTAMATE is released on to AFFERENT neurons leading to the generation of ACTION POTENTIALS.

8.The axons of these neurons form cochlear branch of VESTIBULOCOCHLEAR NERVE.

9.Finally bending of the hair celks in opposite direction slackens the tip links,closes the channels and allow the cells to REPOLARIZE.

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