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anap.com/nnyct/itemView?assignmentProblemiD 911886318offset- prew tied Item 3 e previous 3 of7 I neo Completed Part B There could be many reasons that Marcus may have developed a deep wein thrombosis Cloting homeostasis can be above. For dsrupted at many stops in the pathway example, when blood s stationary, it favors cloting This is a reason that anticoagulants are added to blood collection tubes and that people who are immobile after surgery or with ness are at increased risk f clotting It is also the reason Dr. Xiong asked Marcus about a long flight Blood is returned to the heart through contraction of skeletal muscles compressing veins, and this decreases when we are immobile Blood then pools in the in egs, and ths can promose clotting But not all people develop a dot on long lights, so Marcus might also have other risk factors that contribute to clot For each scenario below, predict what will happen to cloning. Hints Cholesterol deposits cause damage to blood vessel endothellum This would cloting increase 2 Platalets do not express cel-membrane protein that is needed to adhere to subendothelial tissue This would 3 Platelets express extra cell membrane protein that causes planelets to aggregate in the bloodstream This would dlotting 4. Platelets express extra cellmambrane protein that causes platelets to aggregate in the bloodstream This would doning 5 Gene mutation causes a coagulation factor to spend more sme in active form This would clotting 6. Factor needed to convert prothrombin to thrombin is not expressed This would clotting ] cloting 7 Mutation in Sbrinogen does not allow it to be coverted to fibrin This would My Answers Give Up Part C

Explanation / Answer

1. increase (cholestrol is a leading reason for embolic clots due to the same reason)

2. decrease

3. increase

4. increase

5. increase (presence of a clotting factor)

6. decrease (lack of a clotting factor)

7. decrease (lack of a clotting component)

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