1. The disease affecting their patient, providing justification for this diagnos

Question

1. The disease affecting their patient, providing justification for this diagnosis?
2. The relationship between the disease symptoms and the patient’s immune system? 3. Suggested treatments (actual and theoretical) for this disease, including how these treatments would act on the immune system.?

ID equella.federation.edu.au Course: SCMOL 2020 SEM2 2017:I Google Chegg Study Guided Solutions How to take a screenshot on CASE STUDY 6 CLINICAL TEST RESULTS PATIENT DETAILS Name: John Age: 6 years old Blood Analysis Haemoglobin (g/di) Total WBC count (x109/L) John's results 10.4 10.1 Sex: Male Presentation: John presented in the Emergency department with a 2 day history of malaise, fever, blood in his urine and a puffy face. He had no history of renal disease or abdominal trauma. Medical history of note was a sore throat some 12 days before, which had settled without a trip to see his GP His mother remembered that he had received the standard immunization schedule On examination John was febrile, had periorbital and ankle oedema and his blood pressure was 130/90mmHg. The skin on his face and trunk was peeling and he had a reddened tongue. The rest of his examination was unremarkable Urine Analysis Blood present Glucose Ketones Microscopy White, red and granular cells present Throat swab analysis + for Strep. pyogenes Culture

Explanation / Answer

1. The clinical test results indicate that the patient is suffering from Poststreptococcal disorder

2. Poststreptococcal disorder is a group of autoimmune disorders that occur after an infection with the bacteria Streptococcus pyogenes. An autoimmune disorder occurs when your immune system mistakes your healthy cells as foreign invaders and begins to attack them. In poststreptococcal disorders, the antibodies that your immune system created to fight against Streptococcus pyogenes mistakenly start destroying your healthy cells along with the bacteria.

The initial infection might only cause a sore throat, fever, and rash, but poststreptococcal disorders can lead to many different problems. The exact disorder depends on which part of the body is attacked by your immune system. The disorder can affect the kidneys, heart, skin, brain, or joints and may lead to red skin rash, reddened tongue etc. The antibodies may also attack glomeruli leading to blood in the urine (hematuria).

Since there is no cure for the poststreptococcal disorder, treatment is aimed at treating the symptoms. Antibiotics are given to make sure that the Streptococcus pyogenes infection is gone, and also to prevent acute rheumatic fever (ARF). Treatment for ARF includes nonsteroidal anti-inflammatory drugs (NSAIDs).

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