You are running some tests with your new experimental wrinkle reducing drug, cal

Question

You are running some tests with your new experimental wrinkle reducing drug, called NoRaisin. When treating cultured muscle fibers in a dish with NoRaisin, you notice that your cells do not contract when stimulated by an alpha motoneuron; which is ultimately what will reduce wrinkles,so that's good. Additional testing shows that intracellular calcium levels do not increase, even as action potentials are propagated down the entire muscle cell membrane. So what is NoRaisin MOST LIKELY doing? (/2 point) a) the drug stops the sacroplasmic reticulum from working properly b) the drug stops myofilaments from working properly c) the drug stops nicotinic receptors from working properly d) the drug stops the motor end plate from working properly

Explanation / Answer

ANS) Intracellular calcium levels do no increase though action potentials are propagated down the entire muscle cell membrane because NoRaisin:

a) the drug stops the sarocplasmic recticulum from working properly.

Sarcoplasmic recticulum is responsible for the release of calcium ions into the muscles where they bind to actin and myosin filaments for muscular contraction and since in this case its most likely that the drug NoRaisin stops the sarcoplasmic reticulum from working properly due to which there is no increase in intracellular calcium levels seen.

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