#1 The disease diabetes mellitus is due to either destruction of the cells that
ID: 3475971 • Letter: #
Question
#1 The disease diabetes mellitus is due to either destruction of the cells that produce insulin or decrease in sensitivity of target cells to circulate insulin. How would this affect the level of glucose in the body why?
#2 A type of tumor in the pancreas called a glucagonoma and release excess glucagonoma into the blood. How would this affect the level of glucose in the blood? would the overall effect on blood glucose difference from that type 1 diseases mellitus? Why or why not?
#3 In the condition hyperthyroidism, patients have levelvated level of both T3 and T4 due to a malfunction of the immune system that cause the thyroid
gland to overproduce thyroid hormones. Do you think the negative feedback loop would lead to high levels of TSH or low level of TSH? Explain.
Explanation / Answer
(1)
Answer:
When levels of blood sugar rise after a meal the insulin hormone is released and it causes the liver to convert more glucose into glycogen and increases glucose uptake by cells through GLUT4 transporter. This decreases glucose levels in the blood. In the absence of insulin or decreased sensitivity of insulin, there is deregulation of glucose metabolism in the body.
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