DI 5 0.5 Bone tissue (or osseous tissue) is composed of extracellular collage (a
ID: 3475854 • Letter: D
Question
DI 5 0.5 Bone tissue (or osseous tissue) is composed of extracellular collage (a large protein), mineral (calcium salts and other minerals) and bone cells (i.e. osteocytes). Osteogenesis Imperfecta (Ol, aka brittle bone disease) is a congenital bone disorder in which a mutation in the DNA results in a change in one monomer of collagen. Improper formation of collagen fibers leads to an irregular arrangement of osseous tissue. This results in brittle, easily broken bones. To help treat Ol, patients are prescribed dietary supplements with high concentrations of vitamin D, a fat-soluble vitamin. How will the vitamin D cross into the cells lining the Gl tract to be absorbed into the body? Using a transport protein Osmosis Directly through the phospolipid bilayer OHydrolysis D 6 0.5 Bone mass must be maintained to ensure sufficient structural support. Certain bone cells can build and break down bone in response to hormonal changes, but there is no receptor for bone mass. Bone mass is homeostatically regulated. True FalseExplanation / Answer
5.
Vitamin D is fat soluble vitamin that can cross the plasma membrane. Since, plasma membrane is composed of phospholipid bilayer and also it contain cholesterol which enables the diffusion of vitamin D through the lipid bilayer to enter the gastro intestinal tract. Therefore, option 3 is correct.
6.
Bone remodelling and repair processes are homeostatically regulated while maintenance of bone mass depends on dietary and growth factors, hormones and prostaglandins. These factors influence the deposition of minerals on bone and the bone mass. The intestinal absorption of calcium and phosphorus are not homeostatically reguated. Hormone factors like parathyroid, estrogen are regulated by homeostasis. Therefore, bone mass is not homeostatically regulated. The given statement is false.
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