This is the chart. The questions are: A, select the dot number(s) where the foll
ID: 3474247 • Letter: T
Question
This is the chart. The questions are:
A, select the dot number(s) where the following condition is TRUE:
Both Na+ and K+ channels are closed.
1
2
3
4
5
6
7
8
None.
B. select the dot number(s) where the following condition is TRUE:
Na+ channel is INACTIVATED.
1
2
3
4
5
6
7
8
None.
C. select the dot number(s) where the following condition is TRUE:
Na+ channel starting to close, K+ channel still open.
1
2
3
4
6
7
8
None
A, select the dot number(s) where the following condition is TRUE:
Both Na+ and K+ channels are closed.
1
2
3
4
5
6
7
8
None.
B. select the dot number(s) where the following condition is TRUE:
Na+ channel is INACTIVATED.
1
2
3
4
5
6
7
8
None.
C. select the dot number(s) where the following condition is TRUE:
Na+ channel starting to close, K+ channel still open.
1
2
3
4
6
7
8
None
5. For each numbered grey dot on diagram below, indicate the conformational status of the two VOLTAGE dependent channels on the following table. Na+ volt dep nnel volt-dep nnel time pt 6. What would happen to the shape of the action potential (AP) if the sodium channel inactivates bit slower then usual?Explanation / Answer
1 and 8 are the states when the membrane is at rest i.e. before an action potential and after an action potential is completed. At rest, both Na and K channels are closed (So, 1 and 8, both channels closed). When a triggering event happens (mostly a signal from another neuron), Na channels open and the membrane potential slowly start to depolarize (So, at 2 and 3 Na Channel open, K Channel closed), At 4, the K Channels are still closed and sodium channels open but fast reaching saturation. (So at 4, Na Channel open, K channel closed). At 5 action potential is fired and the Na channel starts to be "inactive and close" while K channel is open (repolarization starts). At 6, K channel is open but Na channel is"closed and inactive". At 7 which is the hyperpolarized state, K channels are closing but slow and hence Na channels are now open to regain the resting potential (So At 7 K is open, Na is open). At 8, again both Na and K are closed (after Na channel restores the resting potential)
Now coming to the questions:
A) Both Na+ and K+ channels are closed: 1 and 8
B) Na+ channel is INACTIVATED (100 %): 6
C) Na+ channel starting to close, K+ channel still open: 5
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