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CASE STUDY B Alzheimer Disease Mr. J. is a 75-year-old widower and quite active.

ID: 3458431 • Letter: C

Question

CASE STUDY B Alzheimer Disease Mr. J. is a 75-year-old widower and quite active. He has a history of elevated blood pressure, which he controls effectively with diet and exercise at the local community center. Recently he has been neglecting his appearance and hygiene and his friends at the community center have noted his absence from many activities. He has missed appointments with his nurse practitioner at the local clinic stating that he thought the appointments were "next week." While playing cards with friends, he becomes angry and throws his cards down, saying, "This is a stupid game!" His adult daughter visits him while on a business trip in a nearby city and notes his confusion and irritability When the nurse practitioner refers him to a gerontology assessment . . unit, a preliminary diagnosis of early Alzheimer's disease is made B Y N

Explanation / Answer

1. It is likely that Mr. J’s irritability during playing cards with his peeers is linked to early Alzheimer’s disease. The mood and personalities of people with Alzheimer's can change tremendously. Thus Mr. J too behaves in a way which suggests that he has become confused, suspicious, and anxious. They tends to be easily upset with his friends or in situations where he is out of his comfort zone and cannot control others.

2. Due to early Alzheimer’s disease, Mr. J may experience difficulty in completing familiar tasks such as monitoring his diet and following his exercise routine at the community centre. His gradual decay in remembering his appointment dates can further lead to fluctuations in her BP condition.

People with Alzheimer's often find it hard to complete daily tasks. Sometimes, he may not be able to remember the rules of a favorite game like cards and this could intensify phi’s blood pressure further if he gets irritable during playing with his peers.

3. Elderly like Mr. J with high blood pressure, or hypertension are more likely to have biomarkers of Alzheimer’s in their spinal fluid. What this means is that medication for high blood pressure can also help alleviate some of the more severe symptoms of Alzheimer’s disease and thus Mr. J could benefit from a monitored treatment for his blood pressure as the disease is less likely to progress with certain antihypertensives.

4. A 20% increase in Mr. J’s weight could further exacerbate the fluctuations in his blood pressure and the resulting hypertension and can in turn increase the progression into Alzheimer’s disease.There is an established association between being overweight and developing Alzheimer’s disease.

An increase in weight increases the Body Mass Index of the individual which can lead to greater levels of neurofibrillary tangles – associated with the brains of people with Alzheimer’s disease . Also, Mr. J’s weight gain can Elevate the levels of amyloid in his body. Amyloid is a sticky deposit that accumulates in the brains of people who have Alzheimer’s disease.

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