True or False 1. When comparing adverse events in two study arms, a statisticall

Question

True or False

1. When comparing adverse events in two study arms, a statistically significant result is needed to make determination about safety of intervention

2. Observations that are censored due to withdrawal from the study are excluded from survival analysis.

3. If the 3 year survival probability is 0.3, this means that 70% of patients die (‘fail’) within the first 3 years.

4. If the estimated S(t) = 0.3 at t = 36 months, this means that 30% of patients die (‘fail’) within the first 3 years.

5. If the estimated S(t) = 0.3 at t = 36 months, this means that the 3 year survival probability is 0.3

Explanation / Answer

1. When comparing adverse events in two study arms, a statistically significant result is needed to make determination about safety of intervention. True

2. Observations that are censored due to withdrawal from the study are excluded from survival analysis. True

3. If the 3 year survival probability is 0.3, this means that 70% of patients die (‘fail’) within the first 3 years. False

4. If the estimated S(t) = 0.3 at t = 36 months, this means that 30% of patients die (‘fail’) within the first 3 years. True

5. If the estimated S(t) = 0.3 at t = 36 months, this means that the 3 year survival probability is 0.3 . False

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