Part I-Applying the concept of permeabilities and ion channels to a different ac

Question

Part I-Applying the concept of permeabilities and ion channels to a different action potential Below is the action potential of the cardiac contractlecell. Use the knowledge you just gained from neuronal action potentials to apply to action potential of these cells. Drag and drop the boxes to their appropriate places on the action potential trace. o p P Permeability to ion X Voltage-gated Na channels open +20 2 PK and AP Ca Voltage-gated Na channels closed E -20 voltage-gated Ca channel open APK and P -40 Voltage-gated K S ...60 PNa channels closed -800 Voltage-gated Ca channel closed 100 Voltage-gated K channels open 100 200 300 Time (msec)

Explanation / Answer

1. Voltage gated sodium channels closed (at peak of depolarization).

2. Voltage gated calcium channels open (partial repolarization).

3. Voltage gated potassium channels open (repolarization).

4. Voltage gated sodium channels open (start to depolarize).

0. voltage gated sodium channels open (during the process of depolarization).

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