An investigative team is studying the risk of coronary heart disease associated

Question

An investigative team is studying the risk of coronary heart disease associated with taking postmenopausal hormones among women. They recruited women without coronary heart disease in 3 exposure groups: current use, past use, and never use. They then followed the women over time for incident coronary heart disease. The data collected during the course of the study are in the following table. What is the incidence rate of coronary heart disease among ever users of postmenopausal hormone use? Calculate the incidence rate ratio for the relationship between ever users of postmenopausal hormones compared to never users. Write a 1 sentence numerical interpretation of the incidence rate ratio you calculated in #20. Compare the relationship between current postmenopausal hormone use and coronary heart disease to the relationship past postmenopausal hormone use and coronary heart disease. What is the excess rate of coronary heart disease among never users of postmenopausal hormones compared to ever users?

Explanation / Answer

20) incidence rate per 1000 among ever users = (11+19)/(29922+24386) *1000 =0.552404802

21 ) incidence rate per 1000 among never users = 60/51477 *1000 = 1.16556908

required ratio = 0.552404802 /1.16556908 = 0.47393570

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