A pharmaceutical company is interested in testing their new medication in a phas
ID: 3269666 • Letter: A
Question
A pharmaceutical company is interested in testing their new medication in a phase II clinical trial in order to determine the most effective dosage for reducing fasting glucose. In order to test the medication, there are 3 doses being investigated against a control group receiving best standard of care. Suppose the following ANOVA table summarizes the results of a preliminary analysis among the groups.
Sum of Squares
df
Mean Square
Between Groups
53.2
3
17.73
Within Groups
194.3
247
0.787
Total
247.5
250
A) Assume all conditions for such a procedure are met. Calculate the F statistic and a p-value for the procedure and determine if there is a difference between the groups. Use = 0.05
Sum of Squares
df
Mean Square
Between Groups
53.2
3
17.73
Within Groups
194.3
247
0.787
Total
247.5
250
Explanation / Answer
a) here F stat =MSR/MSE =17.73/0.787 =22.5286
for above test stat and 3,247 degree of freedom in numerator and denominator ; p value =0.0000
as p value is signficantly less then 0.05 level; therefore we have sufficient evidence to conclude that there is a difference between the groups.
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