Which of the following statements describe the Ohno\'s hypothesis regarding the

Question

Which of the following statements describe the Ohno's hypothesis regarding the origin of new genes during evolution? Check all that apply Gene duplication is a source of new genes appearing during evolution if an essential gene is present as a single copy mutations in it are likely to be eliminated by natural selection Copies of essential genes may undergo multiple mutations possibly leading to acquisition of a new function If an essential gene is present as a single copy the gene is likely to be eliminated by natural selection

Explanation / Answer

Answer) Following statements collectively describe the Ohno's hypothesis;

a) Gene duplication is a source of new genes appearing during evolution

b) if an essential gene is present as a single copy mutation in it are likely to be eliminated by natural selection

c) Copies of essential genes may undergo multiple mutations possibly leading to acquisition of a new function

Explanation - Susumu Ohno hypothesized that paleo-ploidy in modern vertebrate genomes has been accomplished due to two complete genome duplication events in the early vertebrate. it suggests that gene duplication provide a source for new genes and new functions as a result of multiple mutations in the duplicated copy of essential genes. but necessarily the mutation in a single copy of gene would be retained in the natural selection and it can not be eliminated for the single copy essential genes.

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