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Use this information to answer the following set of questions: Myasthenia gravis

ID: 323475 • Letter: U

Question

Use this information to answer the following set of questions: Myasthenia gravis (MG) is a severe muscular disorder in which muscles that control the eyelids, facial expressions, swallowing or breathing may be weakened. When breathing muscles are weakened, MG can be fatal. The disease is classified as autoimmune because the person's own antibodies (proteins involved in the immune response to foreign organisms) bind to the body's own acetylcholine receptors, thus blocking the binding of the neurotransmitter acetylcholine. Researchers have observed that women are most likely to develop MG between ages 20-40 whereas men are more likely to develop the disease between 50-70. The binding of the antibodies to acetylcholine receptors will immediately inhibit.... post-synaptic potentials pre-synaptic potentials release of acetylcholine activity of the Na+/K+ pump diffusion of Na+ through Na+ gates

Explanation / Answer

Post Synaptic Potentials.

The Acetylcholine is a neurotransmitter chemical released by the neuron at the terminal endings. Acetylcholine is released in the synaptic junction of neuron and muscle that is known as neuromuscular junction. Acetylcholine has to bind to the acetylcholine receptors present on the muscle membrane of the muscle fibre, after crossing the synapse. When antibodies bind to those receptors, it inhibits the binding of acetylcholine to the reecptors. The binding of antibodies occurs on the surface of muscle fibre, after the synaptic junction, thats why it is called Post Synaptic Potential.

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