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You have identified a temperature-sensitive mutation in yeast (a unicellular euk

ID: 32288 • Letter: Y

Question

You have identified a temperature-sensitive mutation in yeast (a unicellular eukaryote) that prevents the capping of the 5' end of the RNA transcript: Mutant yeast grow only at lower, permissive temperatures. Although you were surprised to find that all of the proteins that make up the capping enzyme complex (CAP) are normal in this mutant strain, you have confirmed that the mutation does affect the RNA polymerase II complex.

What functional component of the RNA pol II complex is likely to be affected by your mutation to account for it's mutant phenotype?

What functional component of the RNA pol II complex is likely to be affected by your mutation to account for it's mutant phenotype?

1) pA 2) SF 3) TF 4) CTD

Explanation / Answer

4) CTD

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