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It is believed that large doses of acetaminophen (the active ingredient in over

ID: 3226530 • Letter: I

Question

It is believed that large doses of acetaminophen (the active ingredient in over the counter pain relievers like Tylenol) may cause damage to the liver. A researcher wants to conduct a study to estimate the proportion of acetaminophen users who have liver damage. If she wants to limit the margin of error of her 95% confidence interval to be no more than 2%, what is the minimum number of subjects that she needs to recruit?

[Note: The researcher has no expectations about what the sample proportion should be ahead of time, so she – and you – should use p = 0.5 to get the most conservative estimate.]

Answer:

Explanation / Answer

here as there is no prior estimation; p=0.5

for 95% CI, z=1.96

and margin of error E =0.02

hence sample size n=p(1-p)*(z/E)2 =~2401

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