(a) A prospective cohort study followed 8,542 women for 10 years to determine if
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Question
(a) A prospective cohort study followed 8,542 women for 10 years to determine if alcohol consumption increased the risk of breast cancer. No statistically significant association was found. Twelve thousand women had been enrolled in the study at its initiation, but 3,458 had withdrawn during the 10-year period. A follow-up of spouses, friends, and relatives of the women who withdrew revealed that more than 60% of the withdrawals had developed breast cancer and that nearly 84% were regular drinkers.
A. Selection Bias
B. Confounding
C. Information Bias
D. Random error
(b) if the answer is A,B or C please briefly provide a rationale for your choice.
Explanation / Answer
a)
Answer: A
That is, selection bias.
b)
Since the selection bias can result when the characteristic of the subjects selected for a study differ systematically from those in the source population.
That is, consider 12000 women had enrolled in the study and around 3458 had withdrawn during the 10 year period. A follow-up process is also failed and yields more than 60% of spouses, friends and relatives had withdrew which all are comes under the follow-up bias. It is a part of selection bias.
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