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Do not solve. Just simply state and explain is this an example of a split plot o

ID: 3221180 • Letter: D

Question

Do not solve. Just simply state and explain is this an example of a split plot or multiple linear regression
A study on mixed species cloning was conducted to test if a non-human donor species could provide an egg for insertion of human dna for the clonal production of human stem cells. So an experiment was conducted in which unfertilized eggs were obtained from two species (pigs and sheep; 3 individuals of each species) and their nucleus was replaced with the nucleus from one of 12 human donors chosen at random. Four eggs from each individual pig or sheep were harvested and their nuclei removed and replaced with human donor nuclei; two from one human and two from another. After the eggs developed, an embryonic stem cell was obtained from each embryo and the number of mutations in a specific gene sequence was determined. Is there a significant difference in the number of mutations between stem cells derived from pigs vs. sheep? How much variation in the number of mutations can be attributed to differences among humans?
species Human # Mutations Pig Pi 11 15 12 14 12 F ta 56 31122256568 13-14 4 7 7 sos-1s-14-11 34 D 1-122334-4556677889_9-10-10-11 001-122 Hd | ec vi 1 1 1 1 2 2 2 2 3 3 3 3 1 1 1 1 2 2 2 2 3 3 33 sp di Pi Pi Pit Pit Pi Pi Pi-Pi Pi-She-She-She-She-Sh Sh Sh Sh Sh Sh Sh Sh

Explanation / Answer

This is a split plot experiment.

There are three factors at play here.

1. Type of species - two levels (pig, sheep)

2. species individual - three levels (1,2,3)

3. Human donor - 12 levels (1,2,3,4...12)

with 2 replications for each combination.

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