8. In Figure 3 , the novel formula is (weight in kilograms = (0.331 × Age in mon
ID: 3202908 • Letter: 8
Question
8. In Figure 3 , the novel formula is (weight in kilograms = (0.331 × Age in months) 6.868. What is the predicted weight in kilograms for a child 10 years old? Show your calculations.
9. Was the sample size of this study adequate for conducting simple linear regression? Provide a rationale for your answer.
10. Describe one potential clinical advantage and one potential clinical problem with using the three novel formulas presented in Figures 1, 2, and 3 in a PICU setting.
Introduction Medications and other therapies often necessitate knowing a patient's weight. However a child may be admitted to a pediatric intensive care unit (PICU) without a known weight and instability and on-going resuscitation may prevent obtaining this needed weight Clinicians would benefit from a tool that could accurately estimate a patient's weight when such information is unavailable. Thus Flannigan et al. (2014) conducted a retro- spective observational study for the purpose of determining "if the revised APLS UK Advanced Paediatric Life Support United Kingdom) formulae for estimating weight are appropriate for use in the paediatric care population in the United Kingdom" (Flannigan et al., 2014, p. 927). The sample included 10,081 children (5,622 males and 4,459 females) who ranged from term-corrected age to 15 years of age, admitted to the PICU during a 5-year period. Because this was a retrospective study, no geographic location, race, and ethnicity data were collected for the sample. A paired samples t-test was used to compare mean sample weights with the APLS UK formula weight. The "APLS UK formula weight F (0.05 x age in months) 4' significantly overestimates the mean weight of children under 1 year admitted to PICU by between 10% and 25.4%" (Flannigan et al, 2014, p 928). Therefore, the researchers concluded that the APLS UK formulas were not appropri- ate for estimating the weight of children admitted to the PICU Relevant Study Results Simple linear regression was used to produce novel formulae for the prediction of the mean weight specifically for the PICU population" (Flannigan et al., 2014, p. 927). The three novel formulas are presented in Figures 1, 2, and 3, respectively. The new formulas calculations are more complex than the APLS UK formulas. "Although a good estimate of mean weight can be obtained by our newly derived formula, reliance on mean weight alone will still result in significant error as the weights of children admitted to PICU in each age and sex gender group have a large standard deviation...Therefore as soon as possible after admission a weight should be obtained, e.g., using a weight be (Flannigan et al., 2014, p. 929)Explanation / Answer
(8) for age=10 years=10*12 months=120 months
weight=0.331*120-6.868=32.852
(9) sample size is adequate
in terms of very rough rules of thumb within the typical context of observational psychological studies involving things like ability tests, attitude scales, personality measures, and so forth, I sometimes think of:
These rules of thumb are grounded in the 95% confidence intervals associated with correlations at these respective levels and the degree of precision that I'd like to theoretically understand the relations of interest. However, it is only a heuristic.
(9) taking age in unit of months is giving better prediction model
age in years should not be taken for prediction of weight
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