6. A rapid diagnostic test has been developed for an emerging tick-borne disease

Question

6. A rapid diagnostic test has been developed for an emerging tick-borne disease that is estimated to infect 10-15% of people in the Northeast United States. The disease is less common in other parts of the county (<3% infected). The rapid diagnostic test has 100% sensitivity and 95% specificity compared to bacterial culture which has been the only way to confirm infection, but is costly and time-consuming. Two primary care clinics - one in Denver, CO and one in Boston, MA – are participating in an implementation study of the new test. Each clinic will use the new test on 500 of their patients. Which clinic will have more false positive tests results?

A. The Denver clinic will have more false positives

B. The Boston clinic will have more false positives

C. Both clinics will have the same number of false positives

D. Neither clinic will have any false positives

Explanation / Answer

Question 6

Specificity = True negative/ (True negative + False Positive)

Here as we know that if there is very less chance of disease to occur that will increase the chance of false positive occurring so here as Boston belong to northeast states that makes it high disease occurring states so it will have less false positive. So, here option A is correct as Denver clinic will have more false positives.

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