The function(s) of the 5\' methyl-G cap on mRNA is(are): (check all that apply)

Question

The function(s) of the 5' methyl-G cap on mRNA is(are):
(check all that apply)

Select one or more:

a. Bind eukaryotic initiation factor 4G (eIF4G)

b. Recruit the large subunit of the ribosome to the 5' end of the mRNA

c. Prevent the degradation of the mRNA by 5' exoribonucleases

d. Ensure that only mRNAs with intact 3' ends are translated.

e. Recruit the small subunit of the ribosome to the 5' end of the mRNA

f. Invoke nonsense mediated decay of the mRNA

g. Bind RNA polymerase II initiation factors to start transcription

h. None of the other choices.

Explanation / Answer

A, C, D, E, F, G all are the functions of the 5' methyl-G cap on mRNA. it is stablizing mRNA, Preventing decayed mRNA to be translated, and responsible for binding of small subunit of the ribosome to the 5' end of the mRNA.

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