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Why are cells growing in a colony on solid media likely to be in many more diffe

ID: 319131 • Letter: W

Question

Why are cells growing in a colony on solid media likely to be in many more different phases of growth than cells growing in liquid culture? Cells grow much more quickly in liquid culture, so they are more likely to stay in the same phase. Cells in liquid culture experience a relatively uniform environment, so they are much more likely to be in the same phase of growth. Growth on solid media provides a greater abundance of nutrients, so cells are able to rapidly separate out into different phases of growth. Unlike cells on the edge of a colony, those in the centre of a colony face depleted levels of nutrients and O_2, yielding different phases of growth.

Explanation / Answer

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