It has been suggested that any male-determining genes contained on the Y chromos
ID: 318304 • Letter: I
Question
It has been suggested that any male-determining genes contained on the Y chromosome in humans cannot be located in the limited region that synapses with the X chromosome (the PARs) during meiosis.
What might be the outcome if such genes were located in this region, i.e. located in the PAR region?
Sex-determining loci on the Y chromosome would be inhibited and no offspring would be produced.
Sex-determining loci on the Y chromosome would be mutated which causes diseases in the offspring.
Sex-determining loci on the Y chromosome would be transferred through crossing over to the X
chromosome
Sex-determining loci on the Y chromosome would be affected and hermaphrodite feature would develop.
a.Sex-determining loci on the Y chromosome would be inhibited and no offspring would be produced.
b.Sex-determining loci on the Y chromosome would be mutated which causes diseases in the offspring.
c.Sex-determining loci on the Y chromosome would be transferred through crossing over to the X
chromosome
Sex-determining loci on the Y chromosome would be affected and hermaphrodite feature would develop.
Explanation / Answer
Option d. Sex-determining loci on the Y chromosome would be affected and hermaphrodite feature would develop.
Structural and/or genetic dissimilarity between the pseudoautosomal regions of the X and Y chromosomes can disrupt pairing and recombination, and consequently cause male infertility.
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