A clinical trial designed to show the eficacy of a new drug in reducing progress
ID: 3173577 • Letter: A
Question
A clinical trial designed to show the eficacy of a new drug in reducing progression to hypertension reports the following:
a) Compute the relative risk of progression to hypertension among patients receiving the new drug as compared to the placebo. b) Compute the difference in proportions of patients progressing to hypertension between the two groups. c) Compute the odds ratio of progression to hypertension among patients receiving the new drug as compared to the placebo.
New Drug Placebo Sample Size 200 200 Progression to hypertension 14% 19%Explanation / Answer
Solution:
a) Compute the relative risk of progression to hypertension among patients receiving the new drug as compared to the placebo.
Ans: 0.7368
b) Compute the difference in proportions of patients progressing to hypertension between the two groups.
Ans: 5%
c) Compute the odds ratio of progression to hypertension among patients receiving the new drug as compared to the placebo.
Ans: 0.694
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