A 4-year old girl presents at the emergency room with bloody diarrhea, fever and

Question

A 4-year old girl presents at the emergency room with bloody diarrhea, fever and vomiting. The ch... A 4-year old girl presents at the emergency room with bloody diarrhea, fever and vomiting. The child’s mother reports that the child has had these symptoms for about 24 hours and she has not passed any urine for about 12 hours. The child is enrolled in a day care center and the group had recently made a field trip to a fast food place to learn about different jobs. The children had a lunch of ground beef, fries and cola after meeting with different workers. This field trip was 4 days earlier on Friday. The child had a temperature of 39C and showed physical signs of dehydration. Blood samples drawn showed evidence of greatly reduced kidney function and lysed red blood cells.

What is your diagnosis here? What microorganism is responsible for this illness?

What pathogenic feature of this organism caused the severity of this problem?

What were the critical features to your diagnosis?

Please cite source**

Explanation / Answer

1)The symptoms resembles the disease hemolytic uremic disease. E.coli is responsible for this illness.

2)E. coli lodge in the digestive tract and produce toxins which enter into the blood stream and thus destroy the R.B.C by travelling through blood stream.

3)Bloody Diarrhea, fever, arresting of urination, vomitting, are the critical features of diagonosis.

Thombocytopenia (low platelet count), Blood urea nitrogen(BUN) and creatinine test should be done to diagonise the critical features of this disease. BUN is done to observe the waste product filtration efficiency of kidney.

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