Name: BS4420 April 6, 2018 3. A mutation from the most prevalent form of a gene

Question

Name: BS4420 April 6, 2018 3. A mutation from the most prevalent form of a gene to a mutant form is called a (0.5 pt) a. forward b. reverse c. wild card d. escalating 4. A mutation that changes the amino acid sequence of the resulting protein by substitution is called a mutation. (0.5 pt) silent None of the choices are correct a. missense c. b. nonsense d. 5. A mutation is one that causes premature termination of the synthesis of the protein product. (0O.5 pt) a. missense b. nonsense silent None of the choices are correct. c. d. 6. Which of the following mutational changes would you predict to be the most and least deleterious to gene function? (2 pts) Insertion of a single nucleotide near the end of the coding sequence. b. a. Removal of a single nucleotide near the beginning of the coding sequence. c. Deletion of three consecutive nucleotides in the middle of the coding sequence. d. Deletion of four consecutive nucleotides in the middle of the coding sequence. e. Substitution of one nucleotide for another in the middle of the coding sequence. The most deleterious is (are) The least deleterious is (are)-- Bonus: (0.5 pt As the result of exposure to a mutagen, cytosine is substituted for thymine in one strand of DNA. Upon subsequent DNA replication, one of the daughter cells will have a GC pair in this position instead of an AT pair. This is called a(n) 1. h. frameshift i. insertion . transition

Explanation / Answer

4) the correct option is option (a) it is a type of the mutations which will be caused by the change in one codon resulting in change in the protein order..

5) the correct option is option (b) nonsense mutations where a single base change results in the formation of the stop codon results in the truncated protein..

6) the correct option is for most deleterious are option (d) where four losses means total loss of protein.. Most least one is option (e) atleast there is a substitute for the previous one..

1) the correct option is option (a) transversion as it means purine gets replaced by a pyramidine ... Transition cannot be the answer as it means purine gets replaced by another purine and pyramidine by another pyramidine..

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