Help me right now please 1. Translate the following mRNA sequences and indicate
ID: 3166135 • Letter: H
Question
Help me right now please1. Translate the following mRNA sequences and indicate the type and consequences of mutations. Mutated sequence could have more than one type of mutation) (3 pts) Original sequence: CUC-UCA-UAU-CCG-CUG-GCU Translation: Mutated sequence 1:GUGAGCUAUCCUUGACU Mutationst Translation Mutated sequence 3: GUCUCAUAUCCCUGACU Mutationls Translation: 2. A change in genotype, but not in phenotype, is most likely due to (0.5 pt) a. a nonsense mutation at the beginning of a gene. b. a point mutation in the third position of a DNA triplet c. a mutation that leads to a frameshift in the middle of a gene. d. thymine dimer formation in the coding region of a gene
Explanation / Answer
Answer:
1).
Original sequence: CUC-UCA-UAU-CCG-CUG-GCU
Translation: Leu – Ser - Tyr – Pro - Leu – Ala
Mutated sequence 1: GUG-AGC-UAU-CCC-UUG-ACU
Translation:----------- Val – Ser – Tyr –Pro – Leu – Thr
Mutation: Silent mutations & Missense mutations
Mutated sequence3: GUC-UCA-UAU-CCC-UGA-CU
Translation:--------- Val - Ser - Tyr - Pro – STOP
Mutation: Nonsense mutations, Silent mutations and missense mutations.
Mutation: Missense mutation (change in the amino acid sequence)
2). b). a point mutation in the third position of a DNA triplet.
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