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hich of the following statements about Vitamin K, EF-hand domains and GLA domain

ID: 3165845 • Letter: H

Question

hich of the following statements about Vitamin K, EF-hand domains and GLA domains re true (indicate all that are true, 5 points) A) Vitamin K is necessary for the y-carboxylation of glutamic acid residues in EF- hand domains Vitamin K is necessary for the y-carboxylation of glutamic acid residues in GLA domains B) C) Vitamin K is an eicosanoid whose binding to a G-protein linked receptor leads to Ca 2 release in the cytoplasm, which calcium binds proteins with GLA domains transcription of calcium binding proteins The ability of Vitamin K to react with molecular oxygen, generating a strong base as an intermediate, is crucial to its activity (E)

Explanation / Answer

The following statements are true:

Vitamin K is necessary for the carboxylation of glutamic acis residues in GLA domains

vitamin K is an eicosanoid whose binding to a G protein linked receptor leads to calcium release in the cytoplasm which calcium binds proteins with GLA domain

the ability of vitamin K to react with molecular oxygen generating a strong base as an intermmediate is crucial to its activity