10. In a normal cell, cell death typically occurs in which phase of the cell cyc
ID: 3165570 • Letter: 1
Question
10. In a normal cell, cell death typically occurs in which phase of the cell cycle? A) G1 B) S C) G2 D) M E) all of the above 11. Which of the following with regard to cancer cells is false ? A) Growth is not regulated by growth factors. B) The cell cycle is disrupted. C) high level of p53 activities is found D) Growth is not stopped by high levels of DNA damage. E) The apoptosis pathway is blocked. 12. The correct order of events in metastasis of a cancer is A) invasion angiogenesis- transportnew site B) transport invasionangiogenesisnew site C) transport angiogenesis- invasionnew site D) angiogenesi E) angiogenesis transport invasion new site is invasion transport new site 13. With regard to cancer cells in the process of metastasis to secondary sites, which of the following statements is not correct? A) If they enter via lymphatics, cancer cells may multiply in regional lymph nodes. B) Many cells from the primary mass may enter circulation. C) The population of cancer cells in the bloodstream all comes from the same clone of cancer cells D) Relatively few cancer cells survive the bloodstream. E) The population of cancer cells is heterogeneous. 14. Some compounds are themselves not carcinogens, but their metabolic activity on the compound produces intermediates that are carcinogenic. This process is known as A) precarcinogenesis. B) carcinogen activation. C) metabolic carcinogenesis. D) plasminogen activation. E) DNA mutagenesis.Explanation / Answer
10. (E) All of the above as there are checkpoints in every phase. If the process is not continue properly then it choose the apoptosis pathway.
11. (C) as high level of p53 induces the pathway that may lead to cell death cell repair.
12. (A) firstly invasion of cancerous cell occurs then angiogenesis means making blood vessel through they may transport to new site.
13. (C) secondary cancer cell are not clone cell they change their habit according to which they going to new site..
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