7. The following pedigree shows inheritance of the inability to smell Pseudomona

Question

7. The following pedigree shows inheritance of the inability to smell Pseudomonas bacteria and the inability to roll the tongue into a U-shape. Inability to roll the tongue is an autosomal recessive trait Use A/a for smelling/non-smelling and R/r for rolling/non-rolling. inability to smell Pseudomonas inability to roll tongue 5 6 7 8 910 Consider the inability to smell Pseudomonas and complete the following conclusions (ignore X-inactivation) [6 pts] (i) The data are consistent/inconsistent with an autosomal dominant mode of inheritance because: (i) The data are consistent/inconsistent with an X-linked recessive mode of inheritance because: (ii) The data are consistent/inconsistent with an X-linked dominant mode of inheritance because: [4 pts] (b) If the two genes are assorting independently, what is the probability that the first child born to 11l-4 and III-5 will be a non-smeller, non-roller?

Explanation / Answer

1. The data inconsistent with an autosomal dominant mode of inheritance because here Trait are skipping the generations. So, it is recessive, not dominant.

2. The data inconsistent with an X-linked recessive mode of inheritance because II 4 and II 5 crossed means all male has to affected. Affected mother will pass the trait on to all their sons.

3. The data inconsistent with an X-linked dominant mode of inheritance because here Trait are skipping the generations. So, it is recessive, not dominant.

B. III4 - Aarr X AaRr III5
   P=3/8

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