2) Substance A is converted to substance B in the body by process X Substance B

Question

2) Substance A is converted to substance B in the body by process X Substance B is converted to substance C in the body by process Y Substance A is not biologically active (has no effect), B is active (has a beneficial effect), and C is not active (has no effect) Processes X and Y can either be inhibited (decreasing conversion) or induced (increasing conversion) When substance A is administered to a patient, which option below will result in the largest biological effect?

(1pts)

Inducing X and inhibiting Y

Inhibiting X and inducing Y

Inducing both processes X and Y

Inhibiting both processes X and Y

3) Drugs A, B, and C are formulated as either tablets, oral solutions, or topical creams. For example: Drug A: tablet Drug B: solution Drug C: topical cream If each dosage form can only be used once, how many additional potential combinations are possible? (1pts)

2

3

4

5

None of the above

4) A 100 mg dose of Drug A causes a reduction in blood pressure. A 200 mg dose of Drug A causes a reduction in blood pressure that is twice that of 100 mg of Drug A. Drug A not able to be absorbed into the body from the stomach, intestines, or anywhere else in the gastrointestinal tract. Oral tablets of Drug A are available as 100 mg, 200 mg, or 300 mg doses. Which of the oral tablets will cause the greatest reduction in blood pressure?

(1pts)

100 mg

200 mg

300 mg

None of the above

5) A patient shows you bottles of medication that she is taking. She takes 12 different medications: 3 medications affect blood pressure 1 medication affects cholesterol 2 medications affect blood sugar 1 medication is a vitamin 2 medications affect mood 1 medication is a hormone 2 medications kill bacteria The medications only affect the processes described (i.e. each medication has only one effect). If you randomly take a bottle from the patient, what are the chances that it will affect blood pressure? (1pts)

1 out of 12

1 out of 4

1 out of 6

1out of 3

None of the above

6) Drugs A, B, and C all act on the the nervous system to decrease conduction: Drug A has no effect unless combined with both Drug B and Drug C Drug B has effect only if both Drug A and Drug C are not present Drug C has no effect unless Drug B is present and only if Drug A is not present Which of the following combinations will result in the greatest total effect?

(1pts)

A and C only

B and C only

A and B only

None of the above

7) All of the following substances have been shown to bind to a target on cellular receptors. These substances are unstable and decompose into inactive substances when heated above the specified temperatures. Which would be the best option to test as a drug candidate?

Substance A: Stable below 25 degrees Celcius (77 degrees Fahrenheit); converted to inactive, non-toxic substance in body

Substance B: Stable below 30 degrees Celcius (86 degrees Fahrenheit); converted to inactive, toxic substance in body

Substance C: Stable below 35 degrees Celcius (95 degrees Fahrenheit); converted to active, toxic substance in body

Substance D: Stable below 40 degrees Celcius (104 degrees Fahrenheit); converted to active, non-toxic substance in body

(1pts)

Substance A

Substance B

Substance C

Substance D

All of the above None of the above

8) Drugs A-D bind to one of the receptors only (1-4): Drug A does not bind to receptors 2 or 4 Drug B binds to receptors 1 or 2 Drug C does not bind to receptors 1 or 3 Drug D binds to receptors 2 or 3 You run an experiment and determine that drug D binds to receptor 2. Match the drugs to the correct receptors. (1pts)

Drug A Select OneReceptor 1Receptor 2Receptor 3Receptor 4

Drug B Select OneReceptor 1Receptor 2Receptor 3Receptor 4

Drug C Select OneReceptor 1Receptor 2Receptor 3Receptor 4

Drug D Select OneReceptor 1Receptor 2Receptor 3Receptor 4

Explanation / Answer

You have written quite a number of questions my friend. As per chegg policy I am supposed to answer just the first one but I will answer 2 if you upvote the answer, I will answer more.

2)

Substance A is not biologically active (has no effect), B is active (has a beneficial effect), and C is not active (has no effect)

A -> B {X}

B -> C {Y}

It is clear that having more B will have more biological effect so the reaction which is creating B (X) should be induced and the reaction depleting/ converting B to C (Y) should be inhibited.

So answer is Inducing X and inhibiting Y.

3)

A, B, C has distinct forms so in total we have 3 forms.

All the 3 forms can be mixed with each other as,

you must have heard of Vitamin E tablets being used with skin cream {so tablet and cream can be combined}

there are tablets which are dissolved in solution first also there are solutions applied along with creams.

so this becomes a question of permutation combination with 3 items.

every form has 2 choices, whether to get included or excluded in the combination -

2 x 2 x 2 = 8

so additionaly 8-3 = 5 combinations can be created.

so the answer is 5 (which is 4th option)

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