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The weak D phenotype is thought to arise from several mechanisms. Which one of t

ID: 314143 • Letter: T

Question

The weak D phenotype is thought to arise from several mechanisms. Which one of the following statements is false?

C gene is in trans position to D gene, this results in a weakening influence on the D gene, examples CDe/Cde and cDe/Cde.

Weak D antigen is genetically transmitted. This can occur rarely in R1 and R2 genotypes in caucasians. Also occurs in the Ro genotype in certain racial groups more commonly.

The D antigen consists of multiple pieces (is a mosaic). Occasionally one or more of these pieces is missing. The red cells are said to have a partial D.

D deletion genes gives rise to weakened expression of D antigen.

Rh null cells lack:

MNSs antigens.

Lewis antigens.

Normal oxygen-carrying capacity.

Rh antigens.

There are two closely related and closely linked genes.

Enzyme techniques, in conjunction with an IgM anti-D.

Increasing the time for the incubation of the saline phase.

Performance of an IAT using an IgG anti-D.

Don't need to do it in a blood bank.


  

C gene is in trans position to D gene, this results in a weakening influence on the D gene, examples CDe/Cde and cDe/Cde.

Weak D antigen is genetically transmitted. This can occur rarely in R1 and R2 genotypes in caucasians. Also occurs in the Ro genotype in certain racial groups more commonly.

The D antigen consists of multiple pieces (is a mosaic). Occasionally one or more of these pieces is missing. The red cells are said to have a partial D.

D deletion genes gives rise to weakened expression of D antigen.

Explanation / Answer

The weak D phenotype is thought to arise from several mechanisms. Which one of the following statements is false?

D deletion genes gives rise to weakened expression of D antigen.

Rh null cells lack:

Rh antigens.

There are two closely related and closely linked genes.

Enzyme techniques, in conjunction with an IgM anti-D.

Increasing the time for the incubation of the saline phase.

Performance of an IAT using an IgG anti-D.

Don't need to do it in a blood bank.

Last one is an incomplete question

D deletion genes gives rise to weakened expression of D antigen.