Suppose that you began a one-year study of tuberculosis (TB) in a subsidized hou

Question

Suppose that you began a one-year study of tuberculosis (TB) in a subsidized housing community in the Lower East Side of New York City on January 1st, 2010. You enrolled 500 residents in your study and checked on their TB status on a monthly basis. At the start of your study on January 1st, you screened all 500 residents. Upon screening, you found 30 residents already had existing cases of TB on January 1st. On February 1st, 5 residents developed TB. On April 1st, 5 more residents developed TB. On June 1st, 10 healthy residents moved away from New York City were lost to follow-up. On July 1st, 10 of the residents who had existing TB on January 1st died from their disease. The study ended on December 31, 2010. Assume that once a person gets TB, they have it for the duration of the study, and assume that all remaining residents stayed healthy and were not lost to follow-up. The case-fatality rate among residents with TB over the course of the year is _____ %. (give number only as percent)

Explanation / Answer

Incidence rate=Number of disease on set/sum of person-time at risk

Now, sum of person-time=healthy person time 9person who remained healthy)+disease person time (person who developed disease)

healthy person time=440*12=5280

disease person time=40*12=480

30/(5280+480)=0.005

denominator=5280+480

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