Match the antibiotic on the left with the correct mechanism of action on the rig

Question

Match the antibiotic on the left with the correct mechanism of action on the right.

       b) inhibits the binding of aminoacyl-tRNAs to the ribosome

Match the antibiotic on the left with the correct mechanism of action on the right.

1) Streptomycin a) binds to 23S RNA 2) Erythromycin

       b) inhibits the binding of aminoacyl-tRNAs to the ribosome

3) Chloramphenicol       c) causes premature chain termination 4) Puromycin d) interferes with normal pairing between aminoacyl-tRNAs and mRNA codon 5) Tetracycline e) blocks elongation by acting as a competitive inhibitor of the peptidyltransferase complex

Explanation / Answer

the correct answer is :

1. streptomycin: interfere with creation of complex between amino acyl trna and mrna

2. erythromycin:it binds to 23S rRNA and interferes with assembly of ribosomes

3. chloramphenicol: blocks the elongation by acting as competitive inhibitor

4. puromycin: causes premature chain termination

5. tetracycline: inhibits binding of aminoacyl trna to the ribosome

therefore the correct choice is : 1-d.2-a,3-e,4-c 5 b

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