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Suppose that we want to determine whether or not amount of light exposure is lin

ID: 3059925 • Letter: S

Question

Suppose that we want to determine whether or not amount of light exposure is linked to depression. We identify 5,000 participants across the United States with no intention of moving to a different permanent residence within the next two years and classify them as living in an area with high or low light exposure. We exclude those who are experiencing depression symptoms at baseline. We then follow them up for two years and determine whether they have experienced depression since baseline. There were 1500 participants residing in low-light areas and 3500 participants living in high-light areas. Of those in low-light areas, 500 participants experienced depression, and of those in high-light areas, 500 participants experienced depression. Assume the exposure is low light. Create a 2x2 table. Calculate the attributable risk (per 1000) and interpret this number.

Explanation / Answer

Result:

Suppose that we want to determine whether or not amount of light exposure is linked to depression. We identify 5,000 participants across the United States with no intention of moving to a different permanent residence within the next two years and classify them as living in an area with high or low light exposure. We exclude those who are experiencing depression symptoms at baseline. We then follow them up for two years and determine whether they have experienced depression since baseline. There were 1500 participants residing in low-light areas and 3500 participants living in high-light areas. Of those in low-light areas, 500 participants experienced depression, and of those in high-light areas, 500 participants experienced depression. Assume the exposure is low light. Create a 2x2 table. Calculate the attributable risk (per 1000) and interpret this number.

Low light

High light

Total

Depression

500

500

1000

No Depression

1000

3000

4000

Total

1500

3500

5000

Risk in low light area = 500/1500=0.33333

Risk in highlight area = 500/3500=0.14286

attributable risk = Risk in low light area - Risk in high light area

= 0.33333-0.14286

=0.19047

attributable risk (per 1000) = 190.47

The difference of experienced depression in 1000 exposed and 1000 unexposed individuals is 190.47.

Low light

High light

Total

Depression

500

500

1000

No Depression

1000

3000

4000

Total

1500

3500

5000

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