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A clinical Trial is conducted comparing a new pain medication for arthritis. Par

ID: 3042944 • Letter: A

Question

A clinical Trial is conducted comparing a new pain medication for arthritis. Participants are randomly assigned to recieve the new medication or a placebo. The outcome is pain relief within 30 minutes. The data are shown below:

Estimate the risk difference in pain relief between treatments?

RD=

Estimate the relative risk in pain relief between treatments?

RR=

Estimate the odds ratio in pain relief between treatments?

OR=

The upper and lower limits of the OR are shown below:

Lower limit of CI: 0.41

Upper Limit of CI: 1.61

Based on the confidence interval values which of the following are true?

A. One can be 95% confident that the true value will be greater than the upper limit

B. One can be 95% confident that the true value will be greater than the lower limit

C. One can be 95% confident that the true value will be between the upper and lower limit

D. A and B

Pain Relief No Pain Relief New Medication 44 76 Placebo 21 99

Explanation / Answer

Risk difference = 44/120-21/120=23/120=0.192

Relative risk = 44/120 / (21/120)=44/21=2.095

Odds ratio = 44/76/(21/99) = 2.729

C. One can be 95% confident that the true value will be between the upper and lower limit

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